Funding
Selected clinical projects of NeuroCure Principal Investigators are supported in the framework of the NeuroCure invitation of tenders for "flexible funds“. This start-up sponsorship is oriented primarily towards “proof-of-concept studies”, which subject fundamental scientific findings to clinical testing for the first time, and in each case it lasts for two years. The submitted applications are evaluated in a competitive, two-stage internal approval procedure.
The sponsored projects include:
in 2010
Baclofen for the treatment of alcohol dependency
A monocentric, randomized, placebo-controlled, double-blind pilot study for the investigation of the efficacy of Baclofen in the prevention of relapses in alcohol-dependent patients.
Study Director: Prof. Dr. Andreas Heinz (Psychiatry CCM)
Clinical establishment of a new kind of classification system for adult Moyamoya Disease.
Study Director: Prof. Dr. Frank Heppner (Neuropathology) in cooperation with Dr. Marcus Czabanka (Neurosurgery CBF)
An exploratory diagnostic study on mutations in PSD associated protein MAGI2 as cause of severe childhood epilepsies.
Study Director: Prof. Dr. Markus Schülke-Gerstenfeld (NCRC, Pediatrics CVK)
Training in older people with disturbed glucose tolerance: advantageous for blood vessels and nerve cells?
A monocentric, prospective, single-blind, randomized, placebo-controlled study for the examination of the effect of "Nordic Walking“ on memory performance and on vascular functions in older people.
Study Director: Prof. Dr. Agnes Flöel (CSB, Neurology CCM)
A proof-of-principle study for the modulation of the congenital immune system using Interferon-beta in patients with clinically isolated syndrome and multiple sclerosis.
Study Director: Prof. Dr. Seija Lehnardt (Neurology CCM) in cooperation with Dr. Klemens Ruprecht (Neurology CCM)
in 2009
Beta-blockers in the treatment of acute ischemic stroke
A randomized, double-blind, placebo-controlled study on the toleration and efficacy of early treatment of stroke patients with beta-blockers. It is intended to prevent both cardiac and infectious complications. You can find more detailed information here.
Study Director: Prof. Dr. Wilhelm Haverkamp (Cardiology CVK) in cooperation with Prof. Dr. Andreas Meisel (NCRC, CSB, Neurology CCM)
Carbon dioxide in the treatment of febrile convulsions
A monocentric, randomized, placebo-controlled, double-blind pilot study for the evaluation of the therapeutic administering of Carbogen for stopping seizures.
Study Director: Prof. Dr. Dietmar Schmitz (NeuroCure, NWFZ) in cooperation with Prof. Dr. Markus Schülke-Gerstenfeld (NCRC, Pediatrics CVK)
Endothelial function and precursor cells in acute ischemic stroke in the framework of the Cream&Sugar study. You can receive more detailed information here.
Study Director: Prof. Dr. Matthias Endres (CSB, Neurology)
Effects of EGCG (epigallocatechin gallate) in Huntington's disease
A multi-center, randomized, placebo-controlled, double-blind study for investigation of the hypothesis that Sunphenon EGCG can improve cognitive performance in patients with Huntington's chorea.
Study Director: Prof. Dr. Josef Priller (Laboratory of Molecularly Psychiatry, Psychiatry CCM) in cooperation with Prof. Dr. Friedemann Paul (NCRC)
Prediction of stroke-associated pneumonias
An observation study on the predictive power of clinical parameters and biomarkers regarding stroke-associated pneumonias. You can receive more detailed information here.
Study Director: Prof. Dr. Andreas Meisel (NCRC, CSB, Neurology CCM)
