Funding

Selected clinical projects of NeuroCure Principal Investigators are supported in the framework of the NeuroCure invitation of tenders for "flexible funds“. This start-up sponsorship is oriented primarily towards “proof-of-concept studies”, which subject fundamental scientific findings to clinical testing for the first time, and in each case it lasts for two years. The submitted applications are evaluated in a competitive, two-stage internal approval procedure.

The sponsored projects include:

in 2010

BACLAD Study

Baclofen for the treatment of alcohol dependency 

A monocentric, randomized, placebo-controlled, double-blind pilot study for the investigation of the efficacy of Baclofen in the prevention of relapses in alcohol-dependent patients.

Study Director: Prof. Dr. Andreas Heinz (Psychiatry CCM)

CLASSIMO Study

Clinical establishment of a new kind of classification system for adult Moyamoya Disease.

Study Director: Prof. Dr. Frank Heppner (Neuropathology) in cooperation with Dr. Marcus Czabanka (Neurosurgery CBF)

Epilepsy Study

An exploratory diagnostic study on mutations in PSD associated protein MAGI2 as cause of severe childhood epilepsies.

Study Director: Prof. Dr. Markus Schülke-Gerstenfeld (NCRC, Pediatrics CVK)

Glucose Tolerance Study

Training in older people with disturbed glucose tolerance: advantageous for blood vessels and nerve cells?

A monocentric, prospective, single-blind, randomized, placebo-controlled study for the examination of the effect of "Nordic Walking“ on memory performance and on vascular functions in older people.

Study Director: Prof. Dr. Agnes Flöel (CSB, Neurology CCM)

 

Interferon-Beta Study

A proof-of-principle study for the modulation of the congenital immune system using Interferon-beta in patients with clinically isolated syndrome and multiple sclerosis.

Study Director: Prof. Dr. Seija Lehnardt (Neurology CCM) in cooperation with Dr. Klemens Ruprecht (Neurology CCM)

in 2009

BIAS Study

Beta-blockers in the treatment of acute ischemic stroke 

A randomized, double-blind, placebo-controlled study on the toleration and efficacy of early treatment of stroke patients with beta-blockers. It is intended to prevent both cardiac and infectious complications. You can find more detailed information here.

Study Director: Prof. Dr. Wilhelm Haverkamp (Cardiology CVK) in cooperation with Prof. Dr. Andreas Meisel (NCRC, CSB, Neurology CCM)

CARDIF Study

Carbon dioxide in the treatment of febrile convulsions 

A monocentric, randomized, placebo-controlled, double-blind pilot study for the evaluation of the therapeutic administering of Carbogen for stopping seizures.

Study Director: Prof. Dr. Dietmar Schmitz (NeuroCure, NWFZ) in cooperation with Prof. Dr. Markus Schülke-Gerstenfeld (NCRC, Pediatrics CVK)

EPCAS Study

Endothelial function and precursor cells in acute ischemic stroke in the framework of the Cream&Sugar study. You can receive more detailed information here.

Study Director: Prof. Dr. Matthias Endres (CSB, Neurology)

ETON Study

Effects of EGCG (epigallocatechin gallate) in Huntington's disease 

A multi-center, randomized, placebo-controlled, double-blind study for investigation of the hypothesis that Sunphenon EGCG can improve cognitive performance in patients with Huntington's chorea.

Study Director: Prof. Dr. Josef Priller (Laboratory of Molecularly Psychiatry, Psychiatry CCM) in cooperation with Prof. Dr. Friedemann Paul (NCRC)

PREDICT Study

Prediction of stroke-associated pneumonias 

An observation study on the predictive power of clinical parameters and biomarkers regarding stroke-associated pneumonias. You can receive more detailed information here.

Study Director: Prof. Dr. Andreas Meisel (NCRC, CSB, Neurology CCM)